Article
Multiple seizure susceptibility genes on chromosome 7 in SWXL-4 congenic mouse strains.
Genomics - 15 Nov 2000
Legare M E, Frankel W N
Abstract excerpt
The SWXL-4 recombinant inbred mouse strain is unusually sensitive to recurrent tonic-clonic seizures upon routine handling and to seizures induced by chemoconvulsants. In a conventional intercross with the ABP/Le strain, we previously mapped a SWXL-4-derived quantitative trait locus called Szf1 (seizure frequency 1) to Chromosome 7. In the present study, we confirm the existence of Szf1 in both an independent...
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