Article
N-ethyl-N-nitrosourea-induced prenatally lethal mutations define at least two complementation groups within the embryonic ectoderm development (eed) locus in mouse chromosome 7.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Jan 1993
Rinchik E M, Carpenter D A
Abstract excerpt
Two loci [l(7)5Rn and l(7)6Rn] defined by N-ethyl-N-nitrosourea (ENU)-induced, prenatally lethal mutations were mapped by means of trans complementation crosses to mice carrying lethal deletions of the albino (c) locus in Chromosome (Chr) 7. Both loci were found to map to the subregion of the Mod...
Topics
- Alleles
- Animals
- Chromosome Mapping
- Crosses, Genetic
- Ectoderm
- Embryonic and Fetal Development
- Ethylnitrosourea
- Female
- Gene Deletion
- Genes, Lethal
- Genetic Complementation Test