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Article

A novel angiogenic effect of PCSK9- regulated genes.

Gene - 5 Feb 2023

Zhan Xiaopeng, Jiang Li, Wang Lufeng, Liu Jiwen, Kang Sheng, Liu Haibo, Lin Li

Abstract excerpt

BACKGROUND: Since the discovery of the Proprotein Convertase Subtilisin/Kexin Type 9(PCSK9) gene has been involved in regulating low-density lipoprotein metabolism and cardiovascular disease (CVD), many therapeutic strategies directly targeting PCSK9 have been introduced. PCSK9 gain of function (GoF) mutations are associated with autosomal dominant hypercholesterolemia (ADH) and premature atherosclerosis. In...

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Identifiers

PMID: 36427678
DOI: 10.1016/j.gene.2022.147051

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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