Article
PCSK9 (Proprotein convertase subtilisin/kexin type 9) inhibitors: past, present, and the future.
European heart journal - 21 Sept 2015
Shimada Yuichi J, Cannon Christopher P
Abstract excerpt
Reduction in low-density lipoprotein cholesterol (LDL-C), mainly with statins, has decreased the risk of cardiovascular events over the last few decades. However, there are several patient populations that warrant further decrease in LDL-C by additional cholesterol-lowering therapy other than statins. Proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors are a new class of drugs that have been shown to...
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