Article

Post-Transcriptional Effects of miRNAs on <em>PCSK7</em> Expression and Function: miR-125a-5p, miR-143-3p and miR-409-3p as Negative Regulators

2022-06-08

Abstract excerpt

The regulatory mechanism of PCSK7 gene is still unknown, although its encoded protein PC7 is the most ancient and highly conserved of all proprotein convertases and exhibits enzymatic and non-enzymatic functions in liver triglyceride regulation. Bioinformatics algorithms were used to predict regulatory microRNAs (miRNAs) of PCSK7 expression. This led to the identification of 4 miRNAs, namely miR-125a-5p, miR-143-3...

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Literature Corpus work: 960fb38b-cbef-5269-aa9f-62efb4e09fbe
DOI: 10.20944/preprints202206.0125.v1

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