Article
Development and metamorphosis in frogs deficient in the thyroid hormone transporter MCT8.
General and comparative endocrinology - 15 Jan 2023
Sterner Zachary R, Jabrah Ayah, Shaidani Nikko-Ideen, Horb Marko E, Dockery Rejenae, Paul Bidisha, Buchholz Daniel R
Abstract excerpt
Precisely regulated thyroid hormone (TH) signaling within tissues during frog metamorphosis gives rise to the organism-wide coordination of developmental events among organs required for survival. This TH signaling is controlled by multiple cellular mechanisms, including TH transport across the plasma membrane. A highly specific TH transporter has been identified, namely monocarboxylate transporter 8 (MCT8),...
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