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Maternal Thyroid Hormones Are Essential for Neural Development in Zebrafish

30 May 2014

Abstract excerpt

Teleost eggs contain an abundant store of maternal thyroid hormones (THs), and early in zebrafish embryonic development, all the genes necessary for TH signaling are expressed. Nonetheless the function of THs in embryonic development remains elusive. To test the hypothesis that THs are fundamental for zebrafish embryonic development, an monocarboxilic transporter 8 (Mct8) knockdown strategy was deployed to...

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PMID: 24877564
DOI: 10.1210/me.2014-1032

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