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Metamorphic gene regulation programs in Xenopus tropicalis tadpole brain

29 Jun 2023

Abstract excerpt

Amphibian metamorphosis is controlled by thyroid hormone (TH), which binds TH receptors (TRs) to regulate gene expression programs that underlie morphogenesis. Gene expression screens using tissues from premetamorphic tadpoles treated with TH identified some TH target genes, but few studies have analyzed genome-wide changes in gene regulation during spontaneous metamorphosis. We analyzed RNA sequencing data at...

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PMID: 37384728
DOI: 10.1371/journal.pone.0287858

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