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Article

Hepatitis C Core Protein Induces a Genotype-Specific Susceptibility of Hepatocytes to TNF-Induced Death In Vitro and In Vivo.

Viruses - 14 Nov 2022

Moustafa Savvina, Kassela Katerina, Bampali Maria, Dovrolis Nikolas, Kakkanas Athanassios, Beloukas Apostolos, Mavromara Penelope, Karakasiliotis Ioannis

Abstract excerpt

Hepatitis C virus (HCV) core protein is a multifunctional protein that is involved in the proliferation, inflammation, and apoptosis mechanism of hepatocytes. HCV core protein genetic variability has been implicated in various outcomes of HCV pathology and treatment. In the present study, we aimed to analyze the role of the HCV core protein in tumor necrosis factor α (TNFα)-induced death under the viewpoint of...

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Identifiers

PMID: 36423130
DOI: 10.3390/v14112521
PMCID: PMC9692671

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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