Article
Modulation of cell death sensitivity by mutant p53 in HCV core-expressing cells.
International journal of molecular medicine - 1 Mar 2005
Cho Jae-We, Park Kun, Kweon Gi Ryang, Park Jong-Chun, Lee Je-Chul, Baek Won-Ki, Jang Byeong-Churl, Suh Seong-Il, Suh Min-Ho
Abstract excerpt
The hepatitis C virus (HCV) core protein plays important roles in hepatocarcinogenesis through modulation of cellular proliferation, apoptosis, and immunological responses. The roles of core protein in apoptosis have been conflicting; both proapoptotic and anti-apoptotic roles have been reported from different experimental conditions. Nonetheless, the overcoming apoptosis is a key molecular event to development...
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