Article
Mutational escape prevention by combination of four neutralizing antibodies that target RBD conserved regions and stem helix.
Virologica Sinica - 1 Dec 2022
Tang Haoneng, Ke Yong, Liao Yunji, Bian Yanlin, Yuan Yunsheng, Wang Ziqi, Yang Li, Ma Hang, Sun Tao, Zhang Baohong, Zhang Xiaoju, Wu Mingyuan, Zhu Jianwei
Abstract excerpt
New variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) appear rapidly every few months. They have showed powerful adaptive ability to circumvent the immune system. To further understand SARS-CoV-2's adaptability so as to seek for strategies to mitigate the emergence of new variants, herein we investigated the viral adaptation in the presence of broadly neutralizing antibodies and their...
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