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Potent and broadly neutralizing antibodies against sarbecoviruses induced by sequential COVID-19 vaccination

6 Feb 2024

Abstract excerpt

The current SARS-CoV-2 variants strikingly evade all authorized monoclonal antibodies and threaten the efficacy of serum-neutralizing activity elicited by vaccination or prior infection, urging the need to develop antivirals against SARS-CoV-2 and related sarbecoviruses. Here, we identified both potent and broadly neutralizing antibodies from a five-dose vaccinated donor who exhibited cross-reactive...

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PMID: 38320990
DOI: 10.1038/s41421-024-00648-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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