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Article

Age at menarche and polycystic ovary syndrome: A Mendelian randomization study

2 May 2023

Abstract excerpt

OBJECTIVE: The authors aimed to use a large two-sample Mendelian randomization (MR) study to reveal the causality between age at menarche (AAM) and polycystic ovary syndrome (PCOS) incidence. METHODS: The authors collected summary statistics from the hitherto largest genome-wide association studies conducted in AAM and PCOS in the same ancestry. MR with inverse variance weighting was conducted as the main...

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PMID: 37128830
DOI: 10.1002/ijgo.14820

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