Article
Age at menarche and cardiovascular risk factors using Mendelian randomization in the Guangzhou Biobank Cohort Study.
Preventive medicine - 1 Aug 2017
Au Yeung Shiu Lun, Jiang Chaoqiang, Cheng Kar Keung, Xu Lin, Zhang Weisen, Lam Tai Hing, Leung Gabriel Matthew, Schooling C Mary
Abstract excerpt
Observational studies show earlier age at menarche associated with higher risk of cardiovascular disease although these studies could be confounded by childhood obesity or childhood socioeconomic position. We tested the hypothesis that earlier age at menarche is associated with poorer cardiovascular risk factors using a Mendelian randomization design. We conducted a Mendelian randomization study in a large...
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