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Cancer-Associated Fibroblasts in Inflammation and Antitumor Immunity

18 Nov 2022

Abstract excerpt

Tumor-associated inflammation (TAI) is a feature of essentially all cancers and can confer both tumor-promoting and -suppressive functions. Cancer-associated fibroblasts (CAF) comprise one very heterogeneous cellular component of the tumor microenvironment characterized by a high degree of plasticity. Recent single-cell sequencing analyses revealed distinct CAF populations in various human cancers and helped to...

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PMID: 36399325
DOI: 10.1158/1078-0432.ccr-22-1031

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