Article
From sentinel cells to inflammatory culprits: cancer-associated fibroblasts in tumour-related inflammation.
The Journal of pathology - 1 Jan 2013
Servais Charlotte, Erez Neta
Abstract excerpt
Inflammation is now established as a hallmark of cancer. Cancer-associated fibroblasts (CAFs) have been established as a key component of the crosstalk between tumour cells and their microenvironment. Central to the role of CAFs in facilitating tumour growth, invasion, and metastasis is their ability to orchestrate tumour-related inflammation. CAFs and their soluble mediators provide multiple complex regulatory...
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