Article
The Validation and Application of a Novel CYP2C19 Genotyping Approach Based on Capillary Electrophoresis in Chinese Han population.
Clinical laboratory - 1 Nov 2022
Chen Dian, Wu Yichen, Wang Yaochen, Yu Hong, Lai Li, Huang Yi
Abstract excerpt
BACKGROUND: CYP2C19 gene polymorphisms have been described to have an important influence on the drug metabolism observed in human populations. A series of PCR-based molecule detection methods are applied to identify CYP2C19 genotype. The aim of the study is to validate the novel CYP2C19 genotyping approach with other methods and reveal the allele frequency distribution of CYP2C19 in Chinese Han population....
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