Article
Comparison of the Microarray-Based Assay, the Real-Time PCR Assay, and the Bidirectional Sequencing Method for CYP2C19 Genotyping.
Clinical laboratory - 1 Jan 2015
Kim Hyun-Ki, Kang Hyun Jung, Ko Dae-Hyun, Jeong Tae-Dong, Lee Woochang, Chun Sail, Min Won-Ki
Abstract excerpt
BACKGROUND: Cytochrome P450 2C19 (CYP2C19) is a clinically important enzyme that metabolizes a wide variety of drugs. Recently, some new genetic assays designed to identify the CYP2C19 genotype were introduced. METHODS: We compared the abilities of the microarray-based Verigene CYP2C19 Test (Nanosphere, USA) and the AccuPower Real-time PCR CYP (*2,*3,*17) assay (Bioneer, Korea) with the ability of the...
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