Article
Investigation of CYP2C19 allele and genotype frequencies in Iranian population using experimental and computational approaches.
Thrombosis research - 1 Feb 2014
Saber Morteza Mahmoudi, Boroumand Mohammadali, Behmanesh Mehrdad
Abstract excerpt
CytochromeP4502C19 is a genetically polymorphic gene with prominent role in drug metabolism. Regarding its critical medical importance, this study was conducted to achieve accurate CYP2C19allele frequencies in Iranian population and hereby paving the way for a tailor-made CYP2C19 DNA test. Iran is a large multi-ethnic country, however, its population structure for CYP2C19 alleles is calculated as nearly zero (Fwc...
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