Article
Identification of two core genes in glioblastomas with different isocitrate dehydrogenase mutation status.
Molecular biology reports - 1 Oct 2020
Guo Yuduo, Wang Xiang, Ning Weihai, Zhang Hongwei, Yu Chunjiang
Abstract excerpt
Glioblastoma (GBM) is one of the most common malignancies of the central nervous system, and the Isocitrate Dehydrogenase (IDH) mutation status of GBM has been recognized as a critical prognostic indicator. However, the molecular mechanism underlying the GBM with different IDH mutation status is still not unclear. In this study, a total of 353 DEGs including 207 up-regulated and 146 down-regulated were screened...
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