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Article

Pleiotropic genetic architecture and novel loci for C-reactive protein levels.

Nature communications - 14 Nov 2022

Koskeridis Fotios, Evangelou Evangelos, Said Saredo, Boyle Joseph J, Elliott Paul, Dehghan Abbas, Tzoulaki Ioanna

Abstract excerpt

C-reactive protein is involved in a plethora of pathophysiological conditions. Many genetic loci associated with C-reactive protein are annotated to lipid and glucose metabolism genes supporting common biological pathways between inflammation and metabolic traits. To identify novel pleiotropic loci, we perform multi-trait analysis of genome-wide association studies on C-reactive protein levels along with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 36376304
DOI: 10.1038/s41467-022-34688-6
PMCID: PMC9663411

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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