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Prioritising determinants of systemic inflammation across molecular, physiological and disease phenotypes

2026-04-14

Abstract excerpt

Systemic inflammation is implicated in various diseases, yet its upstream determinants remain poorly examined. We conducted a large scale two-sample Mendelian randomisation (MR) study to systematically evaluate the potential causal effects of 3,213 molecular (metabolomic, proteomic), physiological and disease traits on circulating interleukin-6 (IL-6) and C-reactive protein (CRP) levels. Genetic instruments were d...

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Literature Corpus work
e4de936f-354b-51ed-8e6b-f655d16490b9
DOI
10.64898/2026.04.10.26350510
Open publication

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Prioritising determinants of systemic inflammation across molecular, physiological and disease phenotypesDOI 10.64898/2026.04.10.26350510
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