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Article

Th2 Cytokines (Interleukin-5 and -9) Polymorphism Affects the Response to Anti-TNF Treatment in Polish Patients with Ankylosing Spondylitis.

International journal of molecular sciences - 29 Oct 2022

Biały Sylwia, Iwaszko Milena, Świerkot Jerzy, Bugaj Bartosz, Kolossa Katarzyna, Jeka Sławomir, Bogunia-Kubik Katarzyna

Abstract excerpt

Ankylosing spondylitis (AS) is an inflammatory disease that belongs to the spondyloarthritis family. IL-5 and IL-9 belong to the group of Th2 cytokines of anti-inflammatory nature. Polymorphisms in their coding genes have been so far associated with various inflammatory diseases, but there are no reports regarding their involvement in AS pathogenesis to date. The purpose of the study was to investigate...

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Identifiers

PMID: 36361964
DOI: 10.3390/ijms232113177
PMCID: PMC9657232

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