Article
Association of TNF-α polymorphism with prediction of response to TNF blockers in spondyloarthritis and inflammatory bowel disease: a meta-analysis.
Pharmacogenomics - 1 Nov 2013
Tong Qiang, Zhao Liang, Qian Xiao-Di, Zhang Lan-Ling, Xu Xia, Dai Sheng-Ming, Cai Qing, Zhao Dong-Bao
Abstract excerpt
AIM: To explore whether TNF-α promoter -308 A/G and -857 C/T polymorphisms have an association with responsiveness to TNF blockers in spondyloarthritis and inflammatory bowel disease. METHODS: A meta-analysis was performed. Pooled odds ratios (ORs) and 95% CIs were calculated. RESULTS: Six relevant studies with a total of 211 spondyloarthritis patients and 392 inflammatory bowel disease patients were included....
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