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Article

The Impact of Anti-TNF Therapy on CD4+ and CD8+ Cell Subsets in Ankylosing Spondylitis.

Pathobiology : journal of immunopathology, molecular and cellular biology - 1 Jan 2018

Dulic Sonja, Vasarhelyi Zsofia, Bajnok Anna, Szalay Balazs, Toldi Gergely, Kovacs Laszlo, Balog Attila

Abstract excerpt

OBJECTIVES: Ankylosing spondylitis (AS) is a chronic, progressive immune-mediated inflammatory disease, driven primarily by Th1 and Th17 cells. Anti-TNF therapies are successfully used in AS to achieve and maintain remission. However, their influence on the composition of T-cell subsets is not clear. We aimed to characterize the changes in the T-cell repertoire after a long-term anti-TNF treatment in AS patients....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Spondylitis, Ankylosing

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Share to T-Lymphocytes, Regulatory

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Source

Identifiers

PMID: 29212085
DOI: 10.1159/000484250

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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