Article
Influence of IL10 (rs1800896) Polymorphism and TNF-α, IL-10, IL-17A, and IL-17F Serum Levels in Ankylosing Spondylitis.
Frontiers in immunology - 1 Jan 2021
Braga Matheus, Lara-Armi Fernanda Formaggi, Neves Janisleya Silva Ferreira, Rocha-Loures Marco Antônio, Terron-Monich Mariana de Souza, Bahls-Pinto Larissa Danielle, de Lima Neto Quirino Alves, Zacarias Joana Maira Valentini, Sell Ana Maria, Visentainer Jeane Eliete Laguila
Abstract excerpt
Ankylosing spondylitis (AS) is a chronic autoimmune inflammatory disease that mainly affects the axial and sacroiliac joints. Single-nucleotide polymorphisms (SNPs) in genes encoding cytokines have been associated with AS, which can interfere with the production of these cytokines and contribute to the development of AS. In order to contribute to a better understanding of the pathology of AS, our objective was to...
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