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Article

Polymorphisms within Genes Coding for IL-17A and F and Their Receptor as Clinical Hallmarks in Ankylosing Spondylitis.

Mediators of inflammation - 1 Jan 2021

Wielińska Joanna, Świerkot Jerzy, Kolossa Katarzyna, Bugaj Bartosz, Chaszczewska-Markowska Monika, Jeka Sławomir, Bogunia-Kubik Katarzyna

Abstract excerpt

IL-17A and IL-17F together with their coreceptor (IL-17RA/RC) were reported to play a significant role in the pathogenesis of spondyloarthritis. The group of axial spondyloarthritis comprises ankylosing spondylitis (AS), a rheumatic disease characterized by chronic inflammation of the joints in the spine. This study is aimed at investigating IL-17A, IL-17F, IL-17RA, and IL-17RC polymorphisms as potential...

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Identifiers

PMID: 34744511
DOI: 10.1155/2021/3125922
PMCID: PMC8566063

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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