Article
Association of interferon regulatory factor 5 (IRF5) gene polymorphisms with juvenile idiopathic arthritis.
Clinical rheumatology - 1 Oct 2018
Esmaeili Reykande Samira, Rezaei Arezou, Sadr Maryam, Shabani Mahsima, Najmi Varzaneh Farnaz, Ziaee Vahid, Rezaei Nima
Abstract excerpt
Interferon regulatory factor 5 (IRF5) is a member of IRF family which induce signaling pathways and are involved in modulation of cell growth, differentiation, apoptosis, and immune system activity. Juvenile idiopathic arthritis (JIA) is an auto-inflammatory syndrome where the inflammatory markers are believed to play a fundamental role in its pathogenesis. In this study, we aimed to assess the association of...
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