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Article

The role of tumor necrosis factor (TNF)-alpha and TNF receptor polymorphisms in susceptibility to ankylosing spondylitis.

Clinical and experimental rheumatology - 1 Jan 2000

Chatzikyriakidou A, Georgiou I, Voulgari P V, Drosos A A

Abstract excerpt

OBJECTIVE: Ankylosing spondylitis (AS) is a chronic inflammatory disease affecting the sacroiliac joint and vertebral column. Tumor necrosis factor alpha (TNF-alpha), a cytokine that acts via two tumor necrosis factor receptors (TNFR1 and TNFR2), may be implicated in the pathogenesis of AS. The aim of the present study was to examine the role of the polymorphisms 36A>G (TNFR1), 676T>G (TNFR2), -857C>T...

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Share to TNF gene
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Restriction Fragment Length

Share to Receptors, Tumor Necrosis Factor, Type I

Share to Receptors, Tumor Necrosis Factor, Type II

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Source

Identifiers

PMID: 19772798

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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