Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

TNF-α and IL10 polymorphisms interaction increases the risk of ankylosing spondylitis in Chinese Han population.

International journal of clinical and experimental pathology - 1 Jan 2015

Wang Nai-Guo, Wang Da-Chuan, Tan Bing-Yi, Wang Feng, Yuan Ze-Nong

Abstract excerpt

AIMS: The target of this article was to reveal the role of tumor necrosis factors α (TNF-α) and Interleukin-10 (IL10) gene polymorphisms in ankylosing spondylitis (AS) development and explore the interaction between these two gene polymorphisms. METHODS: The genotyping of gene polymorphims was conducted using ABI Taqman assay method in 84 AS patients and 92 healthy people. Hardy-Weinberg equilibrium (HWE) was...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent
Share to Asian People

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Case-Control Studies

Share to Genetic Predisposition to Disease

Share to Interleukin-10

Share to Polymorphism, Single Nucleotide

Share to Spondylitis, Ankylosing

Share to Tumor Necrosis Factor-alpha

Source

Open in PubMed Open full text

Identifiers

PMID: 26823867
PMCID: PMC4713653

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

TNF-α and IL10 polymorphisms interaction increases the risk of ankylosing spondylitis in Chinese Han population.PMID 26823867Read ↗

Interleukin-18 Polymorphisms Impose Considerable Impacts on Ankylosing Spondylitis OccurrenceSemantic proximity Read ↗

Associations of Tumor Necrosis Factor Alpha Gene Polymorphisms and Ankylosing Spondylitis Susceptibility: A Meta-analysis Based on 35 Case-control Studies.Semantic proximity Read ↗

Association of IL-1A and IL-1B polymorphisms with ankylosing spondylitis among the Chinese Han population: a case-control study.Semantic proximity Read ↗

[AF4/FMR2 and IL-10 gene single nucleotide polymorphisms are correlated with disease susceptibility and immune infiltration in ankylosing spondylitis].Semantic proximity Read ↗

The association of polymorphisms in TNF and ankylosing spondylitis in common population: a meta-analysis.Semantic proximity Read ↗

Relationship Between IL1 Gene Polymorphism and Susceptibility to Ankylosing Spondylitis: An Updated and Supplemented Meta-Analysis.Semantic proximity Read ↗

The Impact of Promoter Variants in Interleukin-18 on Susceptibility to Ankylosing Spondylitis in a sample of Iraqi PatientsSemantic proximity Read ↗

TNF-α-308 polymorphism determines clinical manifestations and therapeutic response of ankylosing spondylitis in Han Chinese.Semantic proximity Read ↗

The synergistic role of TNFA - 308G/A and IL10 - 1082A/G polymorphisms in ankylosing spondylitis.Semantic proximity Read ↗

The Impact of Promoter Variants in Interleukin-18 on Susceptibility to Ankylosing Spondylitis in a Sample of Iraqi PatientsSemantic proximity Read ↗

Influence of IL10 (rs1800896) Polymorphism and TNF-α, IL-10, IL-17A, and IL-17F Serum Levels in Ankylosing Spondylitis.Semantic proximity Read ↗

The Associations of rs1799724 and rs361525 With the Risk of Ankylosing Spondylitis Are Dependent on HLA-B27 Status in a Chinese Han Population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.