Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Clonal hematopoiesis and atherosclerosis.

The Journal of clinical investigation - 1 Oct 2024

Oren Ohad, Small Aeron M, Libby Peter

Abstract excerpt

Clonal hematopoiesis of indeterminate potential (CHIP) has emerged as a previously unrecognized, potent, age-related, and common risk factor for atherosclerosis. Somatic mutations in certain known leukemia driver genes give rise to clones of mutant cells in peripheral blood. The increased risk of developing hematologic malignancy does not, on its own, explain excess mortality in individuals with CHIP....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Atherosclerosis
Share to Clonal Hematopoiesis
Share to Dioxygenases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA-Binding Proteins

Share to DNA (Cytosine-5-)-Methyltransferases

Share to DNA Methyltransferase 3A

Share to Janus Kinase 2

Share to Proto-Oncogene Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 39352379
DOI: 10.1172/JCI180066
PMCID: PMC11444192

Genes

JAK2
TET2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Clonal hematopoiesis and atherosclerosis.PMID 39352379Read ↗

Clonal hematopoiesis driven by DNMT3A and TET2 mutations: role in monocyte and macrophage biology and atherosclerotic cardiovascular disease.Semantic proximity Read ↗

Somatic Mutations and Clonal Hematopoiesis as Drivers of Age-Related Cardiovascular Risk.Semantic proximity Read ↗

Exploring the Associations Between Clonal Hematopoiesis of Indeterminate Potential, Myeloid Malignancy, and Atherosclerosis.Semantic proximity Read ↗

Clonal Hematopoiesis of Indeterminate Potential: an Expanding Genetic Cause of Cardiovascular Disease.Semantic proximity Read ↗

Clonal hematopoiesis of indeterminate potential (CHIP): Linking somatic mutations, hematopoiesis, chronic inflammation and cardiovascular disease.Semantic proximity Read ↗

Telomere Attrition and Clonal Hematopoiesis of Indeterminate Potential in Cardiovascular Disease.Semantic proximity Read ↗

Clonal hematopoiesis and associated diseases: A review of recent findings.Semantic proximity Read ↗

Clonal Hematopoiesis and Risk of Atherosclerotic Cardiovascular Disease.Semantic proximity Read ↗

Clonal Hematopoiesis and Cardiovascular Diseases: The Connection.Semantic proximity Read ↗

Atherosclerosis and clonal hematopoyesis: A new risk factor.Semantic proximity Read ↗

A new risk factor associated with cardiovascular disease: clonal hematopoiesis of indeterminate potential.Semantic proximity Read ↗

Hematopoiesis of Indeterminate Potential and Atherothrombotic Risk.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.