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Article

Habenula as a Possible Target for Treatment-Resistant Depression Phenotype in Wistar Kyoto Rats.

Molecular neurobiology - 1 Feb 2023

Korlatowicz Agata, Pabian Paulina, Solich Joanna, Kolasa Magdalena, Latocha Katarzyna, Dziedzicka-Wasylewska Marta, Faron-Górecka Agata

Abstract excerpt

The mechanisms of treatment-resistant depression (TRD) are not clear and are difficult to study. An animal model resembling human TRD is the Wistar Kyoto rat strain. In the present study, we focused on selecting miRNAs that differentiate rats of the WKY strain from Wistar Han (WIS) rats in two divisions of the habenula, the lateral and medial (LHb and MHb, respectively). Based on our preliminary study and...

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Identifiers

PMID: 36344870
DOI: 10.1007/s12035-022-03103-y
PMCID: PMC9849162

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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