Article
The Wistar Kyoto Rat: A Model of Depression Traits.
Current neuropharmacology - 1 Jan 2023
Redei Eva E, Udell Mallory E, Solberg Woods Leah C, Chen Hao
Abstract excerpt
There is an ongoing debate about the value of animal research in psychiatry with valid lines of reasoning stating the limits of individual animal models compared to human psychiatric illnesses. Human depression is not a homogenous disorder; therefore, one cannot expect a single animal model to reflect depression heterogeneity. This limited review presents arguments that the Wistar Kyoto (WKY) rats show intrinsic...
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