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Article

Genetic architecture of Wistar-Kyoto rat and spontaneously hypertensive rat substrains from different sources.

Physiological genomics - 2 Jul 2013

Zhang-James Yanli, Middleton Frank A, Faraone Stephen V

Abstract excerpt

The spontaneously hypertensive rat (SHR) has been widely used as a model for studies of hypertension and attention deficit/hyperactivity disorder. The inbred Wistar-Kyoto (WKY) rat, derived from the same ancestral outbred Wistar rat as the SHR, are normotensive and have been used as the closest genetic control for the SHR, although the WKY has also been used as a model for depression. Notably, however,...

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Identifiers

PMID: 23673728
DOI: 10.1152/physiolgenomics.00002.2013
PMCID: PMC3727021

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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