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Article

Dysfunction in fatty acid amide hydrolase is associated with depressive-like behavior in Wistar Kyoto rats.

PloS one - 1 Jan 2012

Vinod K Yaragudri, Xie Shan, Psychoyos Delphine, Hungund Basalingappa L, Cooper Thomas B, Tejani-Butt Shanaz M

Abstract excerpt

BACKGROUND: While the etiology of depression is not clearly understood at the present time, this mental disorder is thought be a complex and multifactorial trait with important genetic and environmental contributing factors. METHODOLOGY/PRINCIPAL FINDINGS: The role of the endocannabinoid (eCB) system in depressive behavior was examined in Wistar Kyoto (WKY) rat strain, a genetic model of depression. Our findings...

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Source

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Identifiers

PMID: 22606285
DOI: 10.1371/journal.pone.0036743
PMCID: PMC3351478

Genes

BDNF
FAAH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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