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Tidy up - The unfolded protein response in sepsis

20 Oct 2022

Abstract excerpt

Pathogens, their toxic byproducts, and the subsequent immune reaction exert different forms of stress and damage to the tissue of the infected host. This stress can trigger specific transcriptional and post-transcriptional programs that have evolved to limit the pathogenesis of infectious diseases by conferring tissue damage control. If these programs fail, infectious diseases can take a severe course including...

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PMID: 36341413
DOI: 10.3389/fimmu.2022.980680

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