Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Role of Protein Ubiquitination in the Onset and Progression of Sepsis

2 Jul 2025

Abstract excerpt

Sepsis is a life-threatening condition characterized by a dysregulated host response to infection, with complex pathophysiological mechanisms. As an important post-translational modification, protein ubiquitination exhibits multiple non-traditional functions in sepsis beyond its conventional role in protein degradation. Regulating the network of inflammatory cytokines, the dynamic balance of immune cells and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autophagy in Disease and Therapy
Share to Immune cells in cancer
Share to Inflammasome and immune disorders

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 40643532
DOI: 10.3390/cells14131012

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 21 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Role of Protein Ubiquitination in the Onset and Progression of SepsisPMID 40643532Read ↗

The role of ubiquitination in microbial infection induced endothelial dysfunction: potential therapeutic targets for sepsisSemantic proximity Read ↗

Pathological roles of ubiquitination and deubiquitination systems in sepsis-induced myocardial dysfunctionSemantic proximity Read ↗

Tidy up - The unfolded protein response in sepsisSemantic proximity Read ↗

Emerging Roles of Non-proteolytic Ubiquitination in TumorigenesisSemantic proximity Read ↗

The ubiquitin codes in cellular stress responsesSemantic proximity Read ↗

Roles of ubiquitin-specific proteases in inflammatory diseasesSemantic proximity Read ↗

The Ubiquitination System within Bacterial Host–Pathogen InteractionsSemantic proximity Read ↗

Ubiquitination in hepatocellular carcinoma immunitySemantic proximity Read ↗

The Ubiquitin–Proteasome System in Immune CellsSemantic proximity Read ↗

Molecular mechanisms and functions of pyroptosis in sepsis and sepsis-associated organ dysfunctionSemantic proximity Read ↗

The ubiquitin proteolytic system and pathogenesis of human diseases: a novel platform for mechanism-based drug targeting.Semantic proximity Read ↗

Linear ubiquitination at a glanceSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.