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Recent Insights into the Role of Unfolded Protein Response in ER Stress in Health and Disease

10 May 2017

Abstract excerpt

Unfolded stress response (UPR) is a conserved cellular pathway involved in protein quality control to maintain homeostasis under different conditions and disease states characterized by cell stress. Although three general schemes of and genes induced by UPR are rather well-established, open questions remain including the precise role of UPR in human diseases and the interactions between different sensor systems...

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PMID: 28540288
DOI: 10.3389/fcell.2017.00048

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