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Article

Novel mutations in TUBB8 and ZP3 cause human oocyte maturation arrest and female infertility.

European journal of obstetrics, gynecology, and reproductive biology - 1 Dec 2022

Li Wenbo, Li Qian, Xu Xiqiao, Wang Chong, Hu Kaiyue, Xu Jiawei

Abstract excerpt

PURPOSE: Variations in many genes may lead to the occurrence of oocyte maturation defectsand female infertility. The objective was to describe newly discovered mutations in TUBB8 and ZP3, and to characterise the accompanying spectrum of phenotypes and modes of inheritance. METHODS: TUBB8 and ZP3 were sequenced from genomic DNA samples extracted from peripheral blood of patients and their family members by the...

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Identifiers

PMID: 36335766
DOI: 10.1016/j.ejogrb.2022.10.017

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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