Oocyte maturation arrest produced by TUBB8 mutations: impact of genetic disorders in infertility treatment.

doi:10.1080/09513590.2020.1725968

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Article

Oocyte maturation arrest produced by TUBB8 mutations: impact of genetic disorders in infertility treatment.

Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology - 1 Sept 2020

Lanuza-López María C, Martínez-Garza Sandra G, Solórzano-Vázquez Jesús F, Paz-Cervantes Daniela, González-Ortega Claudia, Maldonado-Rosas Israel, Villegas-Moreno Gerardo, Villar-Muñoz Lina G, Arroyo-Méndez Francisco A, Gutiérrez-Gutiérrez Antonio M, Piña-Aguilar Raul E

Abstract excerpt

Oocyte maturation defect is a challenging situation in the management of infertility, the etiology may be related to endocrine causes, protocols used in ovarian stimulation, oocyte intrinsic defects or procedures in embryology laboratory. We report three Mexican females in treatment for primary infertility with non-mature oocytes after ovary stimulation and oocyte capture in whom a genetic diagnosis of...

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PMID: 32063091
DOI: 10.1080/09513590.2020.1725968

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