Novel mutations in TRIP13 lead to female infertility with oocyte maturation arrest.

Abstract excerpt

Oocyte maturation arrest (OMA) refers to a rare clinical phenomenon of oocyte maturation disorder caused by abnormal meiosis, which is also one of the primary causes of female infertility. The clinical manifestations of these patients are often characterized with failure to obtain mature oocytes after repeated ovulation stimulation and/or induced in vitro maturation. To date, mutations in PATL2, TUBB8 and TRIP13...

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• Share to ATPases Associated with Diverse Cellular Activities
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