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Article

Lack of causal association between heart failure and osteoporosis: a Mendelian randomization study.

BMC medical genomics - 4 Nov 2022

Chen Heng, Ye Runze, Guo Xiaogang

Abstract excerpt

OBJECTIVES: Heart failure (HF) has been implicated in osteoporosis. However, causality remains unestablished. Here, we sought to assess causal associations of genetic liability to HF with osteoporosis using Mendelian randomization (MR) analyses. METHODS: Independent single nucleotide polymorphisms associated with HF at genome-wide significance were derived from a large genome-wide association study (GWAS)...

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Identifiers

PMID: 36333784
DOI: 10.1186/s12920-022-01385-8
PMCID: PMC9636651

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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