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Article

Exploring causality between bone mineral density and frailty: A bidirectional Mendelian randomization study.

PloS one - 1 Jan 2024

Shen Jue-Xin, Lu Yi, Meng Wei, Yu Lei, Wang Jun-Kai

Abstract excerpt

OBJECTIVE: The bidirectional correlation between low bone mineral density (BMD) and frailty, despite its extensive documentation, still lacks a conclusive understanding. The objective of this Mendelian randomization (MR) study is to investigate the bidirectional causal relationship between BMD and frailty. METHODS: We utilized summary statistics data for BMD at different skeletal sites-including heel BMD (e-BMD,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38271334
DOI: 10.1371/journal.pone.0296867
PMCID: PMC10810463

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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