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Article

Causal Effect of Blood Pressure on Bone Mineral Density and Fracture: A Mendelian Randomization Study.

Frontiers in endocrinology - 1 Jan 2021

He Bin, Yin Lifeng, Zhang Muzi, Lyu Qiong, Quan Zhengxue, Ou Yunsheng

Abstract excerpt

Background: Hypertension may have some association with osteoporosis. This Mendelian randomization (MR) study aimed to explore the causal effect of blood pressure (BP) on bone mineral density (BMD), fall, and fracture. Methods: We used the genome-wide association study (GWAS) summary data among 330,956 European-descent individuals to identify 107 single-nucleotide polymorphisms (SNPs) as the instrumental...

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Identifiers

PMID: 34421826
DOI: 10.3389/fendo.2021.716681
PMCID: PMC8371435

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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