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The causal relationships between body composition and heart failure: A two-sample mendelian randomization study

2 May 2025

Abstract excerpt

The objective of this study was to assess the causal relationships between various body composition indicators, including body mass index (BMI), waist circumference (WC), waist-to-hip ratio (WHR), and specific measures of fat mass (right arm, right leg, trunk, and whole-body fat mass) and fat-free mass, and the risk of heart failure (HF) using a two-sample Mendelian randomization (MR) approach. We used...

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PMID: 40316594
DOI: 10.1038/s41598-025-00406-7

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