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A broadly protective human monoclonal antibody targeting the sialidase activity of influenza A and B virus neuraminidases

3 Nov 2022

Abstract excerpt

Improved vaccines and antiviral agents that provide better, broader protection against seasonal and emerging influenza viruses are needed. The viral surface glycoprotein hemagglutinin (HA) is a primary target for the development of universal influenza vaccines and therapeutic antibodies. The other major surface antigen, neuraminidase (NA), has been less well studied as a potential target and fewer broadly...

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PMID: 36329075
DOI: 10.1038/s41467-022-34521-0

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