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Article

A Human Monoclonal Antibody with Neutralizing Activity against Highly Divergent Influenza Subtypes

5 Dec 2011

Abstract excerpt

The interest in broad-range anti-influenza A monoclonal antibodies (mAbs) has recently been strengthened by the identification of anti-hemagglutinin (HA) mAbs endowed with heterosubtypic neutralizing activity to be used in the design of "universal" prophylactic or therapeutic tools. However, the majority of the single mAbs described to date do not bind and neutralize viral isolates belonging to highly divergent...

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PMID: 22162996
DOI: 10.1371/journal.pone.0028001

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