Article
Human protective monoclonal antibodies against the HA stem of group 2 HAs derived from an H3N2 virus-infected human.
The Journal of infection - 1 Feb 2018
Yamayoshi Seiya, Ito Mutsumi, Uraki Ryuta, Sasaki Tadahiro, Ikuta Kazuyoshi, Kawaoka Yoshihiro
Abstract excerpt
OBJECTIVES: Broadly reactive human monoclonal antibodies against the HA stem of influenza A virus are being developed as therapeutic agents as well as to understand the epitopes that are essential for a universal influenza virus vaccine. METHODS: We isolated and characterized two hetero-reactive human monoclonal antibodies from an H3N2 virus-infected human. RESULTS: These antibodies, which are predominantly bound...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
