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Analysis of the conserved protective epitopes of hemagglutinin on influenza A viruses

16 Feb 2023

Abstract excerpt

The conserved protective epitopes of hemagglutinin (HA) are essential to the design of a universal influenza vaccine and new targeted therapeutic agents. Over the last 15 years, numerous broadly neutralizing antibodies (bnAbs) targeting the HA of influenza A viruses have been isolated from B lymphocytes of human donors and mouse models, and their binding epitopes identified. This work has brought new perspectives...

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PMID: 36875062
DOI: 10.3389/fimmu.2023.1086297

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