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Article

Chimeric 3D gastruloids - a versatile tool for studies of mammalian peri-gastrulation development.

Development (Cambridge, England) - 15 Nov 2022

Wehmeyer Alexandra E, Schüle Katrin M, Conrad Alexandra, Schröder Chiara M, Probst Simone, Arnold Sebastian J

Abstract excerpt

Stem cell-derived three-dimensional (3D) gastruloids show a remarkable capacity of self-organisation and recapitulate many aspects of gastrulation stage mammalian development. Gastruloids can be rapidly generated and offer several experimental advantages, such as scalability, observability and accessibility for manipulation. Here, we present approaches to further expand the experimental potency of murine 3D...

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PMID: 36326003
DOI: 10.1242/dev.200812

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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